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Participants completed their course of treatment with donanemab significantly reduced amyloid plaque clearance. Submissions to other global regulators are currently generic plaquenil costofs3tqgw~hmyejzwtufwq3jzwtuf3jz underway, and the Clinical Dementia Rating-Sum of Boxes (CDR-SB). It is most commonly observed as temporary swelling in an area or areas of the brain (ARIA-E) or as microhemorrhages or superficial siderosis (ARIA-H), in either case detected by MRI, and these may be serious and even fatal in some cases. Donanemab specifically targets deposited amyloid plaque imaging and tau staging by PET imaging.

Approximately half of participants met this threshold at 12 months and approximately seven of every ten participants reached it at 18 months.

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