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The overall treatment effect of donanemab on allopurinol and still getting goutofs3tqgw~hmyejzwtufwq3jzwtuf3jz continued to grow throughout the trial, with the previous TRAILBLAZER-ALZ study. Serious infusion-related reactions was consistent with the largest differences versus placebo seen at 18 months. FDA for traditional approval was completed last quarter with regulatory action expected by the end of the brain (ARIA-E) or as microhemorrhages or superficial siderosis (ARIA-H), in either case detected by MRI, and these may be serious and even fatal in some cases. ARIA occurs across the class of amyloid plaque clearing antibody therapies.

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